Neuropeptide Deep Crease Serum, 1 oz.

$189.00
Size:1.00 oz

Product details

Web ID: 25409545

Targeted skin refinement begins with this Perricone MD Neuropeptide Deep Crease Serum focused on improving the look of lines around the mouth, eyes, lips, and forehead. Neuropeptides and plant stem cells help support wrinkle reduction and improve the appearance of skin density for a smoother look.

  • Product Features

    • WHAT IT IS:
    • A highly-potent silky serum.
    • WHAT IT DOES:
    • Helps smooth the look of even the most stubborn, deep lines, wrinkles, and creases around the mouth, eyes, lips & forehead. Reduces the appearance of deep creases, marionette & lip lines.
    • INGREDIENT HIGHLIGHTS:
    • Formulated with neuropeptides, peptides
    • SKIN TYPES:
    • Suitable for all skin types
    • HOW TO USE:
    • After cleansing, massage onto face & neck using a gentle upward motion. Wait until fully absorbed & follow with your favorite Perricone MD moisturizer. Use morning and evening.

  • Shipping & Returns

    • This item qualifies for Free Shipping with minimum purchase! exclusions & details
    • California and Minnesota customers call 1-800-289-6229 for Free Shipping information.
    • For complete details, see our Shipping and Returns policies.

Ratings & Reviews

Here's what customers think
  • The Neuropeptide Deep Crease Serum is an effective anti-aging product that helps smooth and soften the appearance of deep wrinkles and expression lines.
  • Users reported noticeable improvements in the depth and visibility of lines after consistent use.
  • The serum has a luxurious, silky texture that absorbs quickly without leaving a greasy or sticky residue.
  • It is formulated with neuropeptides, biomimetic growth factor peptides, and plant stem cells to help boost skin elasticity and reduce the look of deep creases.
  • Many users found the serum to be hydrating and leave their skin looking more plump and radiant.
AI-generated summary from 712 customers reviews.
4.5/5

712 star ratings & reviews

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712 reviewssorted by Newest

Meg
8 days ago

Great

I brought a month ago so pleased I did, can notice a bug difference, less deep wrinkles.

Customer review from Perricone MD

Response from Perricone MD

Perricone MD Customer Care7 days ago

That's fantastic to hear! We're so glad you’re seeing a noticeable difference and those deep wrinkles are less visible. Thank you for sharing your experience, your results make us so happy.

BrittaN
13 days ago
Incentivized review

Such a gentle serum- love it!

I tried this serum because of my smile lines and was pleasantly surprised. It’s lightweight but still hydrating and with regular use those lines look a lot softer and less noticeable. My skin feels firmer after all. It’s not an overnight fix but I did see a difference over time.

Customer review from influenster.com

Judy
19 days ago

Wrinkles gone!

I’ve used this wrong mole treatment for almost one year. I’m 83 with hardly a deep wrinkle. It’s a miracle cream!!

Customer review from Perricone MD

Response from Perricone MD

Perricone MD Customer Care19 days ago

We love hearing this—thank you for sharing your experience! So glad it’s been working so wonderfully for you.

AlisaJ
21 days ago
Incentivized review

Gentle results

This serum is a good hydrator to help plump skin and as a result, reduce the visibility of creases. I used it awhile to ensure I could write an informed review, and while it didn’t eliminate any creases (I have one horizontal one on my neck plus deep nasolabial folds, those areas did appear smoother than before. The dropper was a little weird in that I could only get about one drop at a time but I guess it helped not waste product.

Customer review from influenster.com

SarahZ
25 days ago
Incentivized review

High potent results

This high potential deep crease serum if full of super power ingredients, neuro peptides, that helps smooth those pesky wrinkles. It’s a luxury product and you def get the results you’re looking for.

Customer review from influenster.com

LeticiaB
29 days ago
Incentivized review

Does what it says.

I am not new to Perricone MD products, so I was excited to try their deep crease serum. Especially, now that I’m older, I have seen a change in my skin. Especially the elasticity, texture, and increase in fine lines and wrinkles. I have deep smile lines that make my makeup application difficult. Using this product has made them smoother and less noticeable even without makeup use. These pictures are months apart and my no makeup look is much more improved than my makeup look. And this is without consistent nightly use. I’m very pleased with my results.

Customer review from influenster.com

MSL
29 days ago
from Indiana

Noticeable difference

I have been using for about a month and some of the wrinkles I have been concerned about are easing

Recommends this product

Customer review from Perricone MD

Response from Perricone MD

Gabriela28 days ago

Don’t hesitate to share your thoughts any time!

BrittanyQ
1 month ago
Incentivized review

Weightless plumping results

The serum was light weight and absorbed easily. It doesn’t leave any residue on skin and could easily be worn under make up. I have noticed it makes my skin feel more plump. I’m still waiting to see the long term results but I’ve notice some improvement in fine lines.

Customer review from influenster.com