Essential Fx Acyl-Glutathione Deep Crease Serum, 1 fl. oz.

4.4 (761)
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Product details

Web ID: 7009517
This highly-potent serum with a silky, luxurious texture absorbs quickly to smooth even the most stubborn, deep-set lines, wrinkles and creases around the mouth, eyes, lips and forehead, including marionette lines, frown lines, smile lines and nasolabial folds. Over time, these engraved imperfections appear shallower and expression lines appear erased, as the vitamin F blend works to replenish skin's moisture barrier and protect it from environmental aggressors.

  • Product Features

    • SKIN TYPES:
    • Dry skin
    • WHAT IT DOES:
    • Targets deep creases, marionette lines and lip lines
    • Acyl-glutathione helps reduce the look of deep wrinkles and creases by protecting and replenishing fragile skin
    • Vitamin F blend (from flaxseed, chia seed and macadamia seed oils) works over time to restore suppleness and create a healthy glow by intensely moisturizing and improving skin's moisture barrier
    • HOW TO USE:
    • After cleansing, massage onto face and neck using a gentle upward motion
    • Wait until fully absorbed and follow with your favorite Perricone MD moisturizer
    • Use morning and evening

  • Shipping & Returns

    • This item qualifies for Free Shipping with minimum purchase! exclusions & details
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    • This item may not be shipped to California, Colorado, Washington
    • California and Minnesota customers call 1-800-289-6229 for Free Shipping information.
    • This product cannot be shipped to California.
    • This product cannot be shipped to Colorado.
    • For complete details, see our Shipping and Returns policies.
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Ratings & Reviews

Here's what customers think
  • The serum was reported to visibly improve the appearance of fine lines and deep wrinkles, especially around the forehead, eyes, and mouth area, after consistent use for 2-4 weeks.
  • Users praised the lightweight, non-greasy texture that absorbed quickly, leaving the skin feeling soft, hydrated, and radiant.
  • However, some users did not see significant results, and a few felt the product was overpriced and did not meet the claims.
  • Individual results may vary, and consistent use for at least 4 weeks is recommended to see the full benefits.
AI-generated summary from 758 customers reviews.
4.4/5

761 star ratings, 758 reviews

Write a Review
64.3% of reviews have 5 stars
489
22.7% of reviews have 4 stars
173
5.8% of reviews have 3 stars
44
2.6% of reviews have 2 stars
20
4.6% of reviews have 1 star
35

On average, customers rate the Oil-absorbing/moisturizing of this item as Neutral.

On average, customers rate the Heavy/light of this item as Neutral.

On average, customers rate the Best for day/best for night of this item as Best for night.

25 customer images

758 reviews
Andie
6 months ago
from Harrisburg, PA

Smiths and firms

Skin looks and feels smoother almost instantly! The smell is refreshing too!

Recommends this product

Customer review from Perricone MD

Brenda
1 year ago

On average, customers rate the Oil-absorbing/moisturizing of this item as Moisturizing.

On average, customers rate the Heavy/light of this item as Light.

On average, customers rate the Best for day/best for night of this item as Best for night.

Works Great!

This Perricone MD deep crease serum works great! It has nearly erased the deep crease I had above my left brow. I’ve tried other creams and lotions and not one did the trick in making my furrowed brow less so until this little serum came along! I highly recommend! I know it’s pricey, but it beats Botox, which gave me chest pains after just 20 units! Eeek! A sidenote—I do use a generous amount on my face every night after cleansing with Neutrogena Foam Face Cleanser.

On average, customers rate the Oil-absorbing/moisturizing of this item as Moisturizing.

On average, customers rate the Heavy/light of this item as Light.

On average, customers rate the Best for day/best for night of this item as Best for night.

Recommends this product

Helpful?
External reviewer
2 years ago

I think it works.

But I'm not positive. It's hard to compare as I look at my face every day. However the lines above my mouth have almost disappeared. Wish I could see a substantial change in my poor neck but it appears improved. People often say that they can't believe that I am 74.

Recommends this product

Customer review from perriconemd.com

Michele
2 years ago

deep crease serum

WOW! I have never had results like this before! Even my friends noticed and complimented how much better the lines in my forehead look!

Customer review from Perricone MD

Sharon
2 years ago
from Windsor, CO
Verified PurchaserYes

On average, customers rate the Oil-absorbing/moisturizing of this item as Oil-absorbing.

Don't waste your money!

This isn't doing a darn thing...waste of money. I'm surprised they call this a serum. Every serum I've tried was thicker. This looks like watered down milk. I've been using it for a few weeks now hoping to feel/see some results but nothing

On average, customers rate the Oil-absorbing/moisturizing of this item as Oil-absorbing.

Helpful?
External reviewer
2 years ago

Disappointed

I use many products from this line this does absolutely nothing waste of money only botox or surgery is gonna help with deep lines. I will continue to use the other products .not this one

Customer review from perriconemd.com

Judith
2 years ago

DEEP. CREASE BE GONE

I really like and recommend this product. I use it twice a day and I do see a difference!

Customer review from Perricone MD

Sandy
2 years ago

On average, customers rate the Oil-absorbing/moisturizing of this item as Moisturizing.

On average, customers rate the Heavy/light of this item as Light.

On average, customers rate the Best for day/best for night of this item as Best for night.

snake oil

Don’t bother with this overpriced do nothing oil. Sorry I can’t return it.

On average, customers rate the Oil-absorbing/moisturizing of this item as Moisturizing.

On average, customers rate the Heavy/light of this item as Light.

On average, customers rate the Best for day/best for night of this item as Best for night.

Helpful?