Perricone MD
Essential Fx Acyl-Glutathione Deep Crease Serum, 1 fl. oz.

  • Perricone MD - Essential Fx Acyl-Glutathione Deep Crease Serum, 1 fl. oz.
  • Perricone MD - Essential Fx Acyl-Glutathione Deep Crease Serum, 1 fl. oz.
  • Perricone MD - Essential Fx Acyl-Glutathione Deep Crease Serum, 1 fl. oz.
  • Perricone MD - Essential Fx Acyl-Glutathione Deep Crease Serum, 1 fl. oz.
  • Perricone MD - Essential Fx Acyl-Glutathione Deep Crease Serum, 1 fl. oz.
  • Perricone MD - Essential Fx Acyl-Glutathione Deep Crease Serum, 1 fl. oz.
  • Perricone MD - Essential Fx Acyl-Glutathione Deep Crease Serum, 1 fl. oz.

Perricone MD
Essential Fx Acyl-Glutathione Deep Crease Serum, 1 fl. oz.

$179.00

Size: 1.00 oz
In stock: Usually ships within 2 business days.

This item is part of the Perricone MD Fx Acyl-Glutathione Collection

View The Collection
product details

This highly-potent serum with a silky, luxurious texture absorbs quickly to smooth even the most stubborn, deep-set lines, wrinkles and creases around the mouth, eyes, lips and forehead, including marionette lines, frown lines, smile lines and nasolabial folds. Over time, these engraved imperfections appear shallower and expression lines appear erased, as the vitamin F blend works to replenish skin's moisture barrier and protect it from environmental aggressors.

  • SKIN TYPES:
  • Dry skin
  • WHAT IT DOES:
  • Targets deep creases, marionette lines and lip lines
  • Acyl-glutathione helps reduce the look of deep wrinkles and creases by protecting and replenishing fragile skin
  • Vitamin F blend (from flaxseed, chia seed and macadamia seed oils) works over time to restore suppleness and create a healthy glow by intensely moisturizing and improving skin's moisture barrier
  • HOW TO USE:
  • After cleansing, massage onto face and neck using a gentle upward motion
  • Wait until fully absorbed and follow with your favorite Perricone MD moisturizer
  • Use morning and evening
  • Clean ingredients: formulated without parabens, sulfates, mineral oils, silicone, petroleum & phthalates.
  • Web ID: 7009517
Customer Reviews
216 Reviews
5 stars
138
4 stars
50
3 stars
15
2 stars
5
1 star
8
    I hope to never be without this.
    Aug 20, 2020

    Taking advantage of the great deals that occur on this website, I have a variety of the serums, Sub D, moisturizers and use them in different combinations. At 68, I'm loving my skin. When I added the Deep Crease Serum to the areas in need, I really saw a marked improvement. Auto Replenishment, check!

    Customer review from perriconemd.com
    I hope to never be without this.
    by Ceegee from Louisiana

    Taking advantage of the great deals that occur on this website, I have a variety of the serums, Sub D, moisturizers and use them in different combinations. At 68, I'm loving my skin. When I added the Deep Crease Serum to the areas in need, I really saw a marked improvement. Auto Replenishment, check!

    Customer review from perriconemd.com
    Didn't work on my creases, lines or tiny wrinkles
    Aug 16, 2020

    I'm not sure why, but I don't get any kind of results from this product. For reference, I'm 46 and tried this on a chest crease, deep and light wrinkles on my neck, and even on tiny tiny wrinkles on my forehead, but no result anywhere. I put this on fresh clean skin, first thing in the morning, before going to bed, and also during the day. I've almost used the entire bottle, and I've been using it diligently for a few months. However, I will mention that I love Perricone facial moisturizer and will probably never use anything else!

    Response from perriconemd.com
    Aug 19, 2020

    Customer review from perriconemd.com
    Didn't work on my creases, lines or tiny wrinkles
    by Swan from Los Angeles, CA

    I'm not sure why, but I don't get any kind of results from this product. For reference, I'm 46 and tried this on a chest crease, deep and light wrinkles on my neck, and even on tiny tiny wrinkles on my forehead, but no result anywhere. I put this on fresh clean skin, first thing in the morning, before going to bed, and also during the day. I've almost used the entire bottle, and I've been using it diligently for a few months. However, I will mention that I love Perricone facial moisturizer and will probably never use anything else!

    Response from perriconemd.com
    Aug 19, 2020

    Customer review from perriconemd.com
    AMAZING!
    Jun 18, 2020

    So this is my first time trying the deep crease serum but love the sub d products hands down ! But, this product is well worth the extra coin instead of injections or boxtox! I promise! Put it definitely in the creasing area of your neck and just like that they're gone! One day!!! Take a picture if you don't believe me! I'm 45 by the way so I have that creasing in the area where you look down alot and just naturally aging area of the nexk and laugh lines , "What laugh lines?!" Plumped up honey! Im sold! And will scrape every penny to stay with this in my cabinet as long as I live!! Thanks Dr Perricone! You're the best!

    Customer review from perriconemd.com
    AMAZING!
    by Nika from Oakland Ca

    So this is my first time trying the deep crease serum but love the sub d products hands down ! But, this product is well worth the extra coin instead of injections or boxtox! I promise! Put it definitely in the creasing area of your neck and just like that they're gone! One day!!! Take a picture if you don't believe me! I'm 45 by the way so I have that creasing in the area where you look down alot and just naturally aging area of the nexk and laugh lines , "What laugh lines?!" Plumped up honey! Im sold! And will scrape every penny to stay with this in my cabinet as long as I live!! Thanks Dr Perricone! You're the best!

    Customer review from perriconemd.com
    I would buy this product again.
    Jun 13, 2020

    I have been using the Deep Crease Serum for about 4 years alone with the High Potency Amine Face Lift, Cold Plasma Sub-D. I am a 73 year old lady that love love these products. I can really tell the difference in my skin since I started using 4 years ago.

    Customer review from perriconemd.com
    I would buy this product again.
    by Gloria from Undisclosed

    I have been using the Deep Crease Serum for about 4 years alone with the High Potency Amine Face Lift, Cold Plasma Sub-D. I am a 73 year old lady that love love these products. I can really tell the difference in my skin since I started using 4 years ago.

    Customer review from perriconemd.com
    Product excellent, packaging horrible
    Jun 09, 2020

    this product deserves 5 stars, but I can't bring myself to do it. This product is so expensive, but the eyedrop stops working after a while and with a glass container, you can't get it all out. I fell like a good part of my money is wasted.

    Customer review from perriconemd.com
    Product excellent, packaging horrible
    by Colleen from St. Louis

    this product deserves 5 stars, but I can't bring myself to do it. This product is so expensive, but the eyedrop stops working after a while and with a glass container, you can't get it all out. I fell like a good part of my money is wasted.

    Customer review from perriconemd.com
    Great product, but expensive
    May 21, 2020

    This is a great product, you can see a noticeable difference in deep wrinkles with use. I buy it for my Mother in law. Every Christmas and mother's day. I got it for her for mother's day one year, and she asked for more for Christmas, and now it's the only gift she wants. She loves it! She says it keeps her young, she's in her late 60s. I just wish it wasn't so expensive for such a small bottle!

    Customer review from perriconemd.com
    Great product, but expensive
    by J. K. from USA

    This is a great product, you can see a noticeable difference in deep wrinkles with use. I buy it for my Mother in law. Every Christmas and mother's day. I got it for her for mother's day one year, and she asked for more for Christmas, and now it's the only gift she wants. She loves it! She says it keeps her young, she's in her late 60s. I just wish it wasn't so expensive for such a small bottle!

    Customer review from perriconemd.com
    Too much fragrance
    May 02, 2020

    I used this product for a couple years and really liked it. However, the most recent version that I purchased is now heavily perfumed. It is now is a white lotion instead of a clear serum. I cannot use products with fragrance on my face, especially ones with this strong a scent (although it is not an unpleasant scent). Therefore unfortunately I can no longer recommend this serum.

    Response from perriconemd.com
    May 07, 2020

    Customer review from perriconemd.com
    Too much fragrance
    by Marie from Anchorage

    I used this product for a couple years and really liked it. However, the most recent version that I purchased is now heavily perfumed. It is now is a white lotion instead of a clear serum. I cannot use products with fragrance on my face, especially ones with this strong a scent (although it is not an unpleasant scent). Therefore unfortunately I can no longer recommend this serum.

    Response from perriconemd.com
    May 07, 2020

    Customer review from perriconemd.com
    I would, and do, buy this product routinely
    Apr 17, 2020

    I use this product over face and neck every morning. It goes on very smoothly, evens out the creases in and around my chin, and visibly improves the look of my skin. I have used Perricone products since 2003. I am 70 years of age and no one ever guesses anywhere close. My thanks to NV Perricone!

    Customer review from perriconemd.com
    I would, and do, buy this product routinely
    by Poodie from Huntsville, AL

    I use this product over face and neck every morning. It goes on very smoothly, evens out the creases in and around my chin, and visibly improves the look of my skin. I have used Perricone products since 2003. I am 70 years of age and no one ever guesses anywhere close. My thanks to NV Perricone!

    Customer review from perriconemd.com
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